Quotes of the Day

Intermittent fasting is a promising nutritional approach for cancer prevention, as it protects against many of the risk factors such as obesity, type 2 diabetes, and inflammation. Low-carbohydrate diets reduce glucose and insulin, but not the other nutrient sensors, mTOR and AMPK. Fasting simultaneously reduces all the human nutrient sensors and most of the growth pathways, such as PI3K, mTOR, and IGF-1, and also increases autophagy and mitophagy. One recent study found that women who fast for fewer than thirteen hours per night, despite having a lower BMI than other women in the study who fasted for that duration, had a 36 percent higher risk of recurrent breast cancer. [2020] - Jason Fung

The Galleri test looks at methylation patterns of the cell-free DNA, which are basically chemical changes to the DNA molecules that suggest the presence of cancer. In a study, the Galleri test proved to have a very high specificity, about 99.5%, meaning only 0.5% of tests yielded a false positive. If the test says you have cancer, somewhere in your body, then it's likely that you do. The trade-off is that the resulting sensitivity can be low, depending on the stage. (That is, even if the test says you don't have cancer, you're not necessarily in the clear.) Keep in mind this test still has much higher resolution than radiographic tests such as MRI or mammogram. Those imaging-based tests require "seeing" the tumor, which can happen only when the tumor reaches a certain size. With Galleri, the test is looking at cell-free DNA, which can come from any size tumor-even ones that remain invisible to imaging tests. [2023] - Peter Attia

Top-quality marketing requires good-looking graphics. Traditional graphics designers can be quite expensive, so I recommend either finding a friend who is handy with graphics software or using an online vendor. [2006] - Scott Fox

The personal information record is normally kept with your will, for example, in your safety deposit box, with an extra copy kept at home. [2006] - Douglas Gray

Avoid the following vegetable oil: canola/rapeseed oil, soybean oil, corn oil, sunflower oil, safflower oil, and peanut oil. Replace them with coconut oil, animal fats including lard, tallow, butter and ghee, avocado oil, or olive oil. Remove flour, rice, pasta, breads, crackers, and packaged cereals. Replace with carrots, beans, lentils, and chickpeas. [2018] - Steven Lin