Quotes of the Day

Multiple studies in midlife and older adults indicate that sleep disturbance is the risk for late-onset dementia. Note the 7-hour cutoff for association with the lowest hazard ratio. After 7 hours, more sleep is associated with more risk. Other cardiovascular factors are tied to risk of Alzheimer's and all-cause dementia, including a very high HDL, high LDL, and elevation of systolic blood pressure. A retina image is independently helpful for prediction of high risk. Speech, analyzed with AI methods, can predict Alzheimer's disease within 6 years. People deemed at high risk must undergo further assessment and close surveillance. This includes a conventional brain MRI, or a resting-state functional MRI that can further differentiate risk and predict the disease up to 9 years in advance. [2025] - Eric Topol

Immunotherapy has several inherent advantages over conventional treatments. First, the boosted immune system is a dynamic system that can better keep pace with cancer’s moves. Second, the immune system has a memory, so it may prevent recurrence. Third, immunotherapy has fewer side effects than standard chemotherapies. Fourth, immunotherapy is a systemic treatment, which is crucial because cancer is a systemic disease. Affordability, though, is not one of the advantages of immunotherapy. Given the exorbitant price tag of these treatments, many providers question the feasibility of using these advanced drugs. [2020] - Jason Fung

A successful trader is one who is able to apply proven methods with a success rate of about 70%. In fact, some successful traders are very profitable even with a 60% success rate. [2008] - Yeo Keong Hee

It's important to eat organic meats from animals that fed on plants in natural environments (like pasture-raised chickens, cows, and pigs). [2018] - Steven Lin

You can help your negotiation by making it a little more uncomfortable by instituting a penalty whenever the other party asks for a concession. A penalty could be as simple as not responding for several days or requiring your lawyer to look over the issue. This will train the other party to stop asking for concessions, because they'll quickly realize it hurts them every time they do. [2015] - Brandon Turner